Patients with moderate-to-severe atopic dermatitis have shown improvement when treated with dupilumab, a monoclonal antibody that targets the IL-4 receptor a subunit, which inhibits signaling of both IL-4 and IL-13. There are many immune factors that contribute to immune response, but a recent study sought to determine whether dupilumab might affect patients’ responses to commonly …
There are several effective systemic treatments for psoriasis, but deciding which patients may benefit can be a challenge. This is especially true when faced with a group that may not be included in a clinical trial, such as pregnant patients, patients with HIV or hepatitis, and pediatric patients. A new article in a continuing education …
Oral antibiotics are a powerful and effective treatment for acne, but come with potentially serious side effects that may have long-term implications. Therefore, clinicians often seek topical solutions to treat acne as the first-line option. One of the causes of acne is the proliferation of Propionibacterium acnes (P. acnes) bacteria on the skin. Topical solutions …
Hidradenitis suppurativa (HS) is a chronic, autoinflammatory skin disorder that presents with painful, itchy, inflamed nodules, and abscesses. It affects about 1% of the population, more frequently in females, often first appearing in adolescence. First-line therapies include anti-inflammatory oral antibiotics, but more recently treatment with the biologic adalimumab has demonstrated clinically significant improvement in the …