There have been studies that show that pyoderma gangrenosum (PG) may flare up for the first time after a surgical procedure. However, there has been little research on whether the same postoperative risk exists for patients that have a diagnosed history of PG. Knowing the risk may help providers prepare for such an outcome with …
So-called ‘hedgehog pathway inhibitors’ (HPI) such as vismodegib and sonidegib are effective therapies for treating basal cell carcinoma (BCC). HPI target overactive signals in the hedgehog molecular pathway that lead to the proliferation of cancer cells. However, when inhibiting the cancer cells, HPI also inhibit hair follicle (HF) growth which leads to hair loss in …
Forty-two states plus the District of Columbia have laws limiting use of tanning salons by minors. However, even with these regulations in place, nearly 2 million high school students report indoor tanning. Using a phone survey, a recent study sought to determine how often salons in 42 states and the District of Columbia complied with …
Thalidomide shows promise for treating cutaneous lupus erythematosus (CLE) when the first-line treatment has failed. However, thalidomide has its drawbacks, including high cost and high teratogenicity. Clinical benefits must be weighed against potential serious adverse events such as peripheral neuropathy that does not resolve after end of treatment and thromboembolic events. A recent systematic review …
Even though it is well known that using sunscreen reduces risk of skin cancer, the message has not been received by many young people. Use of sunscreen remains low in the adolescent and young adult population. Athletes that spend many outdoor hours during their training are especially at risk due to lengthy exposures to the …
Computers are the future, but does that apply to diagnostic medicine? When it comes to diagnosing melanoma, there is a need and interest in developing a screening procedure that can be used by laypersons and non-dermatologist physicians, as well as improving accuracy for dermatologists. A recent study compared the use of different computer algorithms with …