Do PDE4 Inhibitors Work as Treatment for Hidradenitis Suppurativa?

Hidradenitis suppurativa (HS) is a chronic, autoinflammatory skin disorder that presents with painful, itchy, inflamed nodules, and abscesses. It affects about 1% of the population, more frequently in females, often first appearing in adolescence. First-line therapies include anti-inflammatory oral antibiotics, but more recently treatment with the biologic adalimumab has demonstrated clinically significant improvement in the …