Is Methotrexate Effective to Treat Nummular Eczema in Children?

Nummular eczema (NE) is a form of eczema that is characterized by itchy, oozing, coin-shaped lesions. NE negatively affects quality of life due to a recalcitrant response to topical treatments such as corticosteroids. Low-dose, oral methotrexate has been helpful in treating a number of other chronic inflammatory skin diseases and is generally well-tolerated, and serious …